PRODUCTION PROCESS OF MICROSPHERES

• Main Authors: WATANABE, SUMIO, YAMAKAWA, ICHIRO, MACHIDA, RYOICHI
• Format: Patent
• Language: English
• Published: 01.04.1992
• Edition: 5
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR RELEVANT APPARATUS; TRANSPORTING

Upon formation of a drug into microspheres by O/W solvent evaporation, a mixed solvent of at least one water-insoluble solvent and at least one water-miscible solvent is used as a solvent of an oil phase. A fatty acid or a salt thereof may be added to the mixed solvent. The oil phase may contain at...