PIPERAZINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT

The present invention relates to substituted piperazine derivatives of general formula (I)and to the manufacture of said compounds, pharmaceutical compositions comprising a compound according to general formula (I), and the use of said compounds for the treatment of various medical conditions relate...

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Bibliographic Details
Main Authors ROSENBROCK Holger, GIOVANNINI Riccardo, HOENKE Christoph, SCHMID Bernhard, LESSEL Uta
Format Patent
LanguageEnglish
Russian
Published 30.03.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to substituted piperazine derivatives of general formula (I)and to the manufacture of said compounds, pharmaceutical compositions comprising a compound according to general formula (I), and the use of said compounds for the treatment of various medical conditions related to glycine transporter-1 (GlyT1). Изобретение относится к замещенным производным пиперазина общей формулы (I)и к получению указанных соединений, фармацевтических композиций, содержащих соединение в соответствии с общей формулой (I), и к применению указанных соединений для лечения различных терапевтических состояний, связанных с переносчиком глицина-1 (GlyT1).
Bibliography:Application Number: EA20160000323