LAEGEMIDDELTILBEREDNING TIL INTRAVENOES INJEKTION SAMT FREMGANGSMAADETIL FREMSTILLING HERAF

A medicament formulation of intravenous injection comprising a medicinally active compound, a lipid phase, an emulsifier and water, the lipid phase being present in up to about 30% by weight, the emulsifier being present in about 0.1 to 10% by weight, and water being present up to 100%, the lipid ph...

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Bibliographic Details
Main Author SERNO PETER
Format Patent
LanguageDanish
Published 29.04.1985
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A medicament formulation of intravenous injection comprising a medicinally active compound, a lipid phase, an emulsifier and water, the lipid phase being present in up to about 30% by weight, the emulsifier being present in about 0.1 to 10% by weight, and water being present up to 100%, the lipid phase containing up to about 50% by weight of a sparingly soluble medicinally active compound, and consisting essentially of (a) at least one ester principally of at least one medium chain-length fatty acid, or (b) a mixture of at least one ester principally of at least one medium chain-length fatty acid with at least one vegetable or animal oil, the mixture containing at least 10% by weight of the ester principally of the medium chain-length fatty acid, or (c) at least one ester principally of at least one medium chain-length fatty acid, at least one vegetable or animal oil, or a mixture thereof, in combination with 0.3 to 200% by weight of benzyl alcohol based on the content of lipid or oil. A greater amount of medicinal agent can be administered in a reduced total volume of injectable liquid.
Bibliography:Application Number: DK19840005103