RADIOAKTIVT MÆRKEDE MGLUR2/3-PET-LIGANDER
The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compo...
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| Main Authors | , , , |
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| Format | Patent |
| Language | Danish |
| Published |
02.11.2020
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds. |
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| AbstractList | The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds. |
| Author | VERBEEK, Joost BORMANS, Guy Maurits R VAN GOOL, Michiel Luc Maria ANDRÉS-GIL, José Ignacio |
| Author_xml | – fullname: BORMANS, Guy Maurits R – fullname: ANDRÉS-GIL, José Ignacio – fullname: VERBEEK, Joost – fullname: VAN GOOL, Michiel Luc Maria |
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| Snippet | The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying... |
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| Title | RADIOAKTIVT MÆRKEDE MGLUR2/3-PET-LIGANDER |
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