Mellemprodukter og fremgangsmåde til fremstilling af 18F-mærkede aminosyrer

• Main Authors: Smits, René, Mollitor, Jan, Baumgart, Diana, HOEPPING, Alexander, Müller, Marco, Clausnitzer, Andreas
• Format: Patent
• Language: Danish
• Published: 02.01.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to precursors for the production of optically active 18 F-labelled amino acids bearing the radiochemical label on an aromatic ring, in particular 6-[ 18 F]Fluoro-3,4-dihydroxy-L-phenylalanine ([ 18 F]F-L-DOPA) as well as meta- and para-[ 18 F]Fluoro-L-tyrosine. Further, it rela...