FORBINDELSER OG ANVENDELSE DERAF

Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as beta-lact...

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Main Authors PERIASAMY, Hariharan, BALASUBRAMANIAN, Gopalan, PAUL-SATYASEELA, Maneesh, NARAYANAN, Shridhar, UDAYAMPALAYAM PALANISAMY, Senthilkumar, APPU, Aravind, MANICKAM, Senthilnathan
Format Patent
LanguageDanish
Published 01.03.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as beta-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of beta-lactamases. These compounds restore/potentiate the activities of beta-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting beta-lactamases. Formula (I)
Bibliography:Application Number: DK20110820847T