DI-SUBSTITUEREDE PYRIDINDERIVATER SOM ANTICANCERMIDLER

• Main Authors: OKUNO, MITSUHIRO, KOJIMA, YUTAKA, TAKASU, HIDEKI, MIYAJIMA, KEISUKE, YANAGIHARA, YASUO, YAMADA, SATOSHI, SAKAI, KOJI, OHTSUKA, SHINYA, FUJITA, SHIGEKAZU, SEKIGUCHI, KAZUO, SUGIYAMA, KAZUHISA, SATO, YOSUKE, HIROSE, TOSHIYUKI, SUZUKI, TAKASHI, SUMIDA, TAKUMI, TANAKA, HIDEO
• Format: Patent
• Language: Danish
• Published: 08.12.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides a novel compound having an excellent antitumor effect. The compound of the present invention is represented by the following general formula (1) wherein R1 and R2 are aryl or the like; A is lower alkylene; Ring X is optionally substituted arylene; E is bond or lower al...