IMMUNOGLOBULINFORMULERING OG FREMGANGSMÅDE TIL FREMSTILLING HERAF

A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which m...

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Main Authors O'CONNOR, Barbara, Horsey, Buckley, Shaun E, LEHRMAN, Sherwood, Russ, CALLAWAY, James, Phillips, Christopher, Burke, David J
Format Patent
LanguageDanish
Published 25.06.2018
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
AbstractList A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
Author Buckley, Shaun E
Burke, David J
O'CONNOR, Barbara, Horsey
CALLAWAY, James
LEHRMAN, Sherwood, Russ
Phillips, Christopher
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– fullname: LEHRMAN, Sherwood, Russ
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– fullname: Phillips, Christopher
– fullname: Burke, David J
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Snippet A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title IMMUNOGLOBULINFORMULERING OG FREMGANGSMÅDE TIL FREMSTILLING HERAF
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