Analogifremgangsmåde til fremstilling af et antidiuretisk virksomt polypeptid

• Main Authors: IVAN VAVRA, FRANTISEK SORM, ALENA MACHOVA, MILAN ZAORAL
• Format: Patent
• Language: Danish
• Published: 31.01.1977
• Edition: 2
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

A polypeptide of formula (I):- Mep = beta-mercaptopropionic acid at posn. 1; D-Arg = D-Arginine at posn. 8 The new polypeptide has greater specific anti-diuretic activity and may be used for the regulation or polyuria and reduction of polydypsia in Diabetes insipidus. R' = benzyl R"= p-tol...