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The invention concerns a method of comparative high-throughput screening of pharmacologically active substances. In one process step the substances are deposited on test cells that contain one or more biological target molecules, the cells having an identical biological base composition and differin...

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Bibliographic Details
Main Authors WEYER-CZERNILOFSKY, ULRIKE, LOEBER, GERHARD, VON RUEDEN, THOMAS, TONTSCH, ULRIKE, SCHNITZER, RENATE, WICHE-CASTANON, MARIA, JOSEFA, CZERNILOFSKY, ARMIN, PETER, METZ, THOMAS, STRATOWA, CHRISTIAN, HIMMLER, ADOLF, SPEVAK, WALTER
Format Patent
LanguageDanish
Published 01.12.2003
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:The invention concerns a method of comparative high-throughput screening of pharmacologically active substances. In one process step the substances are deposited on test cells that contain one or more biological target molecules, the cells having an identical biological base composition and differing in their target molecules, and/or are deposited on cells having a different biological base composition and identical target molecules. The effect of the substance on the activity of the target molecules is measured using a detection system linked to the activation of the target molecule and is compared directly with the effect on other molecules.
Bibliography:Application Number: DK19970930400T