Bionedbrydelig partikelforming vektor og fremgangsmåde til fremstilling deraf

A biodegradable particulate vector is disclosed and is characterized in that it comprises: a nucleus consisting of a cross-linked polysaccharide or oligosaccharide matrix to which ionic ligands are attached; a first semi-permeable lipid layer linked to the nucleus by covalent bonds; a second layer o...

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Main Authors DELRIEU, PASCAL, SAMAIN, DANIEL, DE MIGUEL, IGNACIO, DING, LI, RIEUMAJOU, VALERIE, IOUALALEN, KARIM, CERVILLA, MONIQUE, IMBERTIE, LAURENT, MENIALI, JAOUAD
Format Patent
LanguageDanish
Published 03.11.1997
Edition6
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Summary:A biodegradable particulate vector is disclosed and is characterized in that it comprises: a nucleus consisting of a cross-linked polysaccharide or oligosaccharide matrix to which ionic ligands are attached; a first semi-permeable lipid layer linked to the nucleus by covalent bonds; a second layer of amphiphilic compounds linked to the first lipid layer by hydrophobic interactions. A method for synthesis of said vector is also disclosed.
Bibliography:Application Number: DK19920911799T