Verwendung von 5-Acyl-1,4-dihydropyridinen

• Main Authors: SOMMERMEYER, HENNING., 51061 KOELN, DE, GLASER, THOMAS., 51491 OVERATH, DE, WITTKA, REILINDE., 51069 KOELN, DE, URBAHNS, KLAUS., 42327 WUPPERTAL, DE, HEINE, HANS-GEORG., 47800 KREFELD, DE, VRY, JEAN DE., 51503 ROESRATH, DE
• Format: Patent
• Language: German
• Published: 20.06.1996
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The use of 1-alkyl-3,5-diacyl-2,6-dimethyl-6-aryl-1,4-dihydropyridines of formula (I) is claimed in the prepn. of selective potassium channel modulating medicaments for treating CNS disorders. R1 = 6-10C aryl (opt. substd. by 1-5 of NO2, CN, halogen, CF3 and 1-6C alkylthio); R2 = 1-8C alkyl, phenyl,...