POLYPEPTID MIT ANTIVIRALER WIRKUNG, UND SEINE ANWENDUNG

• Main Author: NATORI, SHUNJI, TONE-MACHI KITA-SOMA-GUN IBARAGI-KEN, JP
• Format: Patent
• Language: German
• Published: 04.02.1993
• Edition: 5
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

A biologically active polypeptide, method of obtaining same and use thereof are disclosed. The polypeptide is obtained through steps of cultivating a cell line established from Sarcophaga peregrina embryo to produce the same in a culture medium, as product of the cell line, isolating and purifying the same. The polypeptide shows an anti-virus activity, and has the following formula H--Ala-Thr-Cys-Asp-Leu-Leu-Ser-Gly-Thr-Gly-Ile-Asn-His-Ser-Ala-Cys-Ala -Ala-His-Cy s-Leu-Leu-Arg-Gly-Asn-Arg-Gly-Gly-Tyr-Cys-Asn-Gly-Lys-Ala-Val-Cys-Val- Cys-Arg-Asn.