PRAEPARAT ZUR PERKUTANEN VERABREICHUNG VON ARZNEIMITTELN UND VERFAHREN ZU DESSEN HERSTELLUNG

A percutaneous absorption type preparation and a process for preparing the same, where the preparation comprises a backing readily conformable to the skin or mucosa and substantially impermeable to a drug absorbed through the skin or mucosa, and an adhesive layer provided on a backing, where the adh...

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Main Authors TOKUDA,SHOICHI, ITO,YUUSUKE, KINOSHITA,TAKASHI, SHIBATA,KEISUKE, OTSUKA,SABURO
Format Patent
LanguageGerman
Published 12.09.1985
Edition4
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A percutaneous absorption type preparation and a process for preparing the same, where the preparation comprises a backing readily conformable to the skin or mucosa and substantially impermeable to a drug absorbed through the skin or mucosa, and an adhesive layer provided on a backing, where the adhesive layer comprises a polymer which is pressure-adhesive at room temperature and the drug present in the polymer, wherein the amount of the drug present in the adhesive layer is greater than its saturated solubility in the polymer is dispersed in the polymer in the form of recrystallized fine particles. The excess portion is again dissolved in the polymer when the drug is consumed as the result of absorption through the skin or mucosa. The drug is released continuously over a long period of time.
Bibliography:Application Number: DE19853500508