VERFAHREN ZUR HERSTELLUNG VON 5-ETHYL-4-(2-PHENOXYETHYL)-2H-1,2,4-TRIAZOL-3-(4H)-ON, ZWISCHENPRODUKT UND VERFAHREN ZU DESSEN HERSTELLUNG

• Main Author: D. MADDING,GARY
• Format: Patent
• Language: German
• Published: 20.06.1985
• Edition: 3
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

In a novel process for the preparation of 5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazolone (used in the synthesis of antidepressant 1,2,4-triazolones typified by 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one, also known as nefazodone), novel interme...