DE2833892

This invention relates to novel dibenzo[d,g][1,3,6]dioxazocine derivatives represented by the general formula I (I) wherein R1 and R2 independently represent hydrogen, halogen, cyano or trifluoromethyl, Y stands for hydrogen or a group of formula wherein A stands for a straight or branched chained a...

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Main Authors KOSOCZKY, IBOLYA, PETOECZ, LUJZA, GRASSER, KATALIN, NAGY, JOZSEF, BUDAPEST, HU, KISZELLY, ENIKOE, ROZSA, LASZLO
Format Patent
LanguageEnglish
Published 07.08.1986
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention relates to novel dibenzo[d,g][1,3,6]dioxazocine derivatives represented by the general formula I (I) wherein R1 and R2 independently represent hydrogen, halogen, cyano or trifluoromethyl, Y stands for hydrogen or a group of formula wherein A stands for a straight or branched chained alkylene having from 2 to 5 carbon atoms and R3 and R4 independently stand for an alkyl having from 1 to 4 carbon atoms, or R3 and R4 together with the nitrogen atom they are attached to and optionally together with a further nitrogen atom or with an additional oxygen atom may form a five- or six-membered heterocyclic ring optionally substituted with an alkyl having from 1 to 4 carbon atoms, and pharmaceutically acceptable acid addition salts thereof formed with an inorganic or organic acid. A process for the preparation of these compounds is also within the scope of this invention. The above compounds possess valuable pharmaceutical properties, for instance they are effective local anaesthetics and can be used for treating Parkinson syndrome.
Bibliography:Application Number: DE19782833892