PROSTANSAEUREDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

Prostanoic acid derivatives of the formula, [I] wherein R1 is hydrogen or C1-4 alkyl, R2 is C4-8 alkyl and >C=Z is >C=O or are prepared by reacting a cyclopentane of the formula, wherein R2 is defined above and R is hydrogen or tetrahydropyranyl, with Wittig reagent of the formula, (R3)3P=CH(C...

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Bibliographic Details
Main Authors SUGIE,AKIHIKO, KATSUBE,JUNKI, SHIMOMURA,HIROMI
Format Patent
LanguageGerman
Published 14.12.1978
Edition2
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Prostanoic acid derivatives of the formula, [I] wherein R1 is hydrogen or C1-4 alkyl, R2 is C4-8 alkyl and >C=Z is >C=O or are prepared by reacting a cyclopentane of the formula, wherein R2 is defined above and R is hydrogen or tetrahydropyranyl, with Wittig reagent of the formula, (R3)3P=CH(CH2)3COOM wherein R3 is aryl and M is alkali metal and, if necessary, hydrolyzing, or by oxidizing a compound of the formula, wherein R1 and R2 are as defined above and R9 is tetrahydropyranyl group, with an oxidizing agent. The compounds (I) are useful as anti-ulcer agent.
Bibliography:Application Number: DE19782823551