Tricyclic inhibitors of poly(ADP-ribose)polymerases

Compounds of the formula shown below are poly(ADP-ribosyl)transferase inhibitors:Such compounds are useful as therapeutics in treating cancers and in ameliorating the effects of stroke, head trauma, and neurodegenerative disease.

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Bibliographic Details
Main Authors MARAKOVITS JOSEPH TIMOTHY, TIKHE JAYASHREE GIRISH, EASTMAN BRIAN WALTER, SKALITZKY DONALD JAMES, KUMPF ROBERT ARNOLD, WEBBER STEPHEN EVAN
Format Patent
LanguageCzech
English
Published 14.08.2002
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula shown below are poly(ADP-ribosyl)transferase inhibitors:Such compounds are useful as therapeutics in treating cancers and in ameliorating the effects of stroke, head trauma, and neurodegenerative disease.
Bibliography:Application Number: CZ20020000613