SOLVATO ACETONICO DEL DIMETOXI DOCETAXEL Y SU PROCEDIMIENTO DE PREPARACION

The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent clai...

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Bibliographic Details
Main Authors MARC-ANTOINE PERRIN, ERIC DIDIER
Format Patent
LanguageSpanish
Published 15.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent claim is included for the preparation of (A). ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given in the source material.
AbstractList The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert. butoxycarbonylamino-2-hydroxy-3-phenylpropionate (I) (i.e. dimethoxy docetaxel) (preferably containing 5-7 wt. % acetone) is new. An independent claim is included for the preparation of (A). ACTIVITY : Cytostatic. MECHANISM OF ACTION : None given in the source material.
Author ERIC DIDIER
MARC-ANTOINE PERRIN
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Snippet The acetone solvate (A) of 4-acetoxy-2alpha -benzoyloxy-5beta ,20-epoxy-1-hydroxy-7beta ,10beta -dimethoxy-9-oxo-tax-11-en-13alpha -yl (2R,3S)-3-tert....
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title SOLVATO ACETONICO DEL DIMETOXI DOCETAXEL Y SU PROCEDIMIENTO DE PREPARACION
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