Non-invasive brain injury diagnosis device

• Main Authors: VALIMAA LASSE, HAREL ADRIAN
• Format: Patent
• Language: Chinese; English
• Published: 10.11.2020
• Subjects: DIAGNOSIS; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; PHYSICS; SURGERY; TESTING

Provided herein is a non-invasive brain injury diagnostic device that performs a non-invasive diagnostic test in a subject suspected of having a brain injury. A device for diagnosing brain injury in asubject includes a detector of a porous matrix, an indicator formulation disposed on the porous matrix and comprising at least one lectin and/or antibody capable of selectively binding to a glycan-based biomarker indicative of brain injury in a sample, and a visual detectable marker; and a handle in communication with the detector, where at least one of the lectin and/or antibody and/or the visually detectable marker is immobilized in and/or on a detection zone in the porous matrix, and the visually detectable marker exhibits a color intensity level after a binding event of the glycan-based biomarker with the lectin and/or antibody and becomes visible. 本文提供一种在怀疑患有脑损伤的受试者中进行非侵入性诊断测试的非侵入性脑损伤诊断装置。用于诊断受试者的脑损伤的装置包括多孔基质的探测器，指示剂制剂，所述指示剂制剂设置在所述多孔基质上并且包含能够选择性结合指示样品中的脑损伤的基于聚糖的生物标志物的至少一种凝集素和/或抗体，以及视觉可检测标记；和与所述探测器连通的手柄，其中所述凝