Reagent kit for detecting hepatitis B virus e antigen and use

• Main Authors: JING CAIYING, SUN BING, YAN LINGCHEN, HUANG CHAOFENG, CAI XINGFENG
• Format: Patent
• Language: Chinese; English
• Published: 18.05.2011
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The present invention relates to a reagent kit for detecting hepatitis B virus e antigen and its use, and relates to the immunological virus detecting technology field. In order to overcome the technique defects of high false positive rate and low sensitivity in the HBeAg detection by using a coating monoclonal antibody and an enzyme labeled multi-resistance ELISA in the prior art, the invention provides the reagent kit for detecting the hepatitis B virus e antigen and its use, as well as the application in the HBeAg detection. The invention discloses the reagent kit for detectiong the hepatitis B virus e antigen, characterized by including monoclonal antibodies packed in containers to distinguish different epitopes of the hepatitis B virus e antigen, optionally one antibody labeled with horseradish peroxidase or fluorescein isothiocyanate or biotin. The reagent kit of the present invention is used clinically in detecting the hepatitis B virus, and has high specificity, sensitivity up to ng level, and excelle