Inhibitors of AKT activity
The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer c...
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| Main Author | |
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| Format | Patent |
| Language | English |
| Published |
04.04.2007
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. |
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| AbstractList | The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention. |
| Author | BILODEAU MARK T.,CHEN CHIXU,COSFORD NICHOLAS D. P.,EASTMAN BRIAN W.,HARTNETT JOHN C.,HU ESSA H.,MANLEY PETER J.,NEILSON LOU ANNE,TEHRANI LIDA R.,WU ZHICAI |
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| Snippet | The present invention is directed to compounds which contain substituted napthyridines which inhibit the activity of Akt, a serine/threonine protein kinase.... |
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| Title | Inhibitors of AKT activity |
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