Compositions of lipopeptide antibiotic derivatives and methods of use thereof

The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatme...

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Main Author CAMERON DALE R.,BOYD VINCENT A.,LEESE RICHARD A.,CURRAN WILLIAM V.,BORDERS DONALD B.,SGARBI PAULO W. M.,WACOWICH-SGARBI SHIRLEY A.,NODWELL MATTHEW,CHEN YUCHEN,JIA QI,DUGOURD DOMINIQUE
Format Patent
LanguageEnglish
Published 27.09.2006
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of microbial infections.
Bibliography:Application Number: CN200480020655