Indoor air pollutant vulcabone intoxicating mechanism research

• Main Author: YUBIN JI
• Format: Patent
• Language: English
• Published: 16.02.2005
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COLORIMETRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT,POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED,VISIBLE OR ULTRA-VIOLET LIGHT; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; RADIATION PYROMETRY; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to intoxicating mechanism research, of indoor air pollutant toluene diisocyanate, and is aimed at researching the absorption, distribution, excretory condition and metabolic mechanism, pathway and metallic product of the toluene diisocyanate in animal body and main metabolic targent organ, and utilizing RT-PCR method and combining it with laser cofocal scanning technique and digital image processing system to research the influence of toluene diisocyanate and metabolic product on target cell receptor and gene expression, revealing intoxicating mechanism of said compound from molecular level and providing scientific theoretical basis for ecological risk assessment, environment law enforcement and defining prophylactico-therapeutic measures.