Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derilatives as IP antagonists

• Main Authors: C. O'YANG, D. NITZAN, F.J. LOPEZ-TAPIA
• Format: Patent
• Language: Chinese; English
• Published: 08.09.2004
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

本发明涉及通常作为IP受体拮抗剂且由通式(I)所示的化合物，其中G#+[1]选自基团a、b#+[1]和b#+[2]；(式a、b#+[1]和b#+[2])以及A和G#+[2]如说明书中所定义；或其单个的异构体、异构体的外消旋或非外消旋混合物或其可药用盐或溶剂化物。本发明还涉及含有该类化合物的药物组合物、其用作治疗剂的用途及其制备方法。 This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: wherein G1 i...