3-thiazol-4-yl-pyprolidine derivatives as AMP-specific phosphodiesterase inhibitors

Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is...

Full description

Saved in:
Bibliographic Details
Main Authors K.W. FOWLER, J. ODINGO
Format Patent
LanguageEnglish
Published 06.08.2003
Edition7
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
AbstractList Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
Author K.W. FOWLER
J. ODINGO
Author_xml – fullname: K.W. FOWLER
– fullname: J. ODINGO
BookMark eNqFyr0KwjAUhuEMOvh3DeYGMmg6dC1FcVEE3UtMvpIDIQk5oVCvXgd3h5dneddiEVPESjy0qp7MOwXVqDmoPOeSAjmKkA6FJlNpAkvDsrveFWdYGsnK7BN_cwSuKIYhKXp6UU2Ft2I5msDY_dyI_fn07C8KOQ3gbCwi6tDfDo1u2qPu9P_jA62yOaA
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
Edition 7
ExternalDocumentID CN1434823A
GroupedDBID EVB
ID FETCH-epo_espacenet_CN1434823A3
IEDL.DBID EVB
IngestDate Fri Jul 19 14:20:07 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CN1434823A3
Notes Application Number: CN20008019121
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030806&DB=EPODOC&CC=CN&NR=1434823A
ParticipantIDs epo_espacenet_CN1434823A
PublicationCentury 2000
PublicationDate 20030806
PublicationDateYYYYMMDD 2003-08-06
PublicationDate_xml – month: 08
  year: 2003
  text: 20030806
  day: 06
PublicationDecade 2000
PublicationYear 2003
RelatedCompanies ICOS CORP
RelatedCompanies_xml – name: ICOS CORP
Score 2.581552
Snippet Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 3-thiazol-4-yl-pyprolidine derivatives as AMP-specific phosphodiesterase inhibitors
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20030806&DB=EPODOC&locale=&CC=CN&NR=1434823A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3fS8MwED7mFPVNpzJ_90H6FtzWrqwPRbZ0ZQjthk7Z20jXlBZGW2xV9K_3Lqzqyx4CIYGQhLvcJfm-O4C7MEYh6YSCdSNhMDOmRO54t2Wia6IA4WG4ksR39gNr8mI-LvqLBiQ1F0bFCf1UwRFRo1ao75U6r4u_RyxXYSvL-zDFpvzBmzuuXt-ODXSALN0dOePZ1J1ynXOHB3rw5KBbYA56xnAHdsmJpij749cRcVKK_wbFO4K9GY6VVcfQkFkLDnidd60F-_7muxurG80rT-DZYFWSiu98zUz2tWYFUZXWKVoeqUUoRR8qgHepiVIb-jNGBEoCAWlFkpdYCCtIXONSammWpGFKSXZO4dYbz_mE4eyWvxux5EG9DOMMmlmeyTZotrRFbFidQUSflANpy07PllEciV43ljI8h_a2US62d13CoYKtETjCuoJm9fYur9H8VuGN2rkfMUCMNw
link.rule.ids 230,309,786,891,25594,76903
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3fS8MwED7mFOebTmX-XB-kb8FtrXV9KLKlG1XXruiUvY10TWlhtMVWRf96L2FVX_YQCAmEJNzlcsn33QFcBREKSSdgpBsyjeiRSOSOvi1hXR0FCA_DJRd8Z9cznBf9YX4zr0FccWFknNBPGRwRNWqJ-l7K8zr_e8SyJbayuA4SbMruxjPLVivvWMMLkKHaQ2vkT-0pVSm1qKd6TxZeC_R-TxtswfYtOoTSUXodCk5K_t-gjPdhx8ex0vIAajxtQoNWedeasOuuv7uxuta84hCeNVLGCfvOVkQnXyuSC6rSKkHLw5UQpehDBvAuFFYoA9cngkApQEBKHmcFFoEVFFzjgitJGidBIpLsHEF7PJpRh-DsFr8bsaBetQztGOpplvIWKCY3WaQZnX4oPin73OSdnsnDKGS9bsR5cAKtTaOcbu5qQ8OZuZPF5N57PIM9CWETQAnjHOrl2zu_QFNcBpdyF38A5OaPIQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=3-thiazol-4-yl-pyprolidine+derivatives+as+AMP-specific+phosphodiesterase+inhibitors&rft.inventor=K.W.+FOWLER&rft.inventor=J.+ODINGO&rft.date=2003-08-06&rft.externalDBID=A&rft.externalDocID=CN1434823A