Benzothiophenecarboxamide derivatives and PGD2 antagonists comprising them

PCT No. PCT/JP97/04527 Sec. 371 Date May 17, 1999 Sec. 102(e) Date May 17, 1999 PCT Filed Dec. 10, 1997 PCT Pub. No. WO98/25919 PCT Pub. Date Jun. 18, 1998A compound, a pharmaceutically acceptable salt thereof, or a hydrate thereof having PGD2-antagonistic activities, inhibitory activities against i...

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Bibliographic Details
Main Authors HIRAMATSU YOSHIHARU, ARIMURA AKINORI, HONMA TSUNETOSHI
Format Patent
LanguageEnglish
Published 05.01.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/JP97/04527 Sec. 371 Date May 17, 1999 Sec. 102(e) Date May 17, 1999 PCT Filed Dec. 10, 1997 PCT Pub. No. WO98/25919 PCT Pub. Date Jun. 18, 1998A compound, a pharmaceutically acceptable salt thereof, or a hydrate thereof having PGD2-antagonistic activities, inhibitory activities against infiltration of eosinophils, and being useful as a drug for treating diseases, such as systemic mastocytosis and disorder of systemic mast cell activation, as well as tracheal contraction, asthma, allergic rhinitis, allergic conjunctivitis, urticaria, ischemic reperfusion injury, inflammation and atopic dermatitis, which is shown by the following formula (I): is provided
Bibliography:Application Number: CN19971080628