Application of FGL1 protein in preparation of kit for diagnosing allergic rhinitis

• Main Author: LIU SHIJIA
• Format: Patent
• Language: Chinese; English
• Published: 11.04.2025
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention discloses application of FGL1 protein in preparation of a kit for diagnosing allergic rhinitis. It is found that the FGL1 protein content in the serum of a healthy subject and the FGL1 protein content in the serum of an allergic rhinitis patient are obviously different, and the FGL1 protein content in the serum of the allergic rhinitis patient is obviously higher than that of the healthy subject. A further diagnosis efficacy test shows that the FGL1 protein can effectively diagnose and distinguish healthy subjects and allergic rhinitis patients, the diagnosis accuracy is high, the FGL1 protein can be used for developing a kit for diagnosing allergic rhinitis, and the objectivity is obviously improved compared with an existing diagnosis method. 本发明公开了一种FGL1蛋白用于制备诊断过敏性鼻炎的试剂盒的用途。本发明发现，健康受试者和过敏性鼻炎患者血清中的FGL1蛋白含量存在明显差异，过敏性鼻炎患者血清中的FGL1蛋白含量明显高于健康受试者。进一步的诊断效能试验显示，FGL1蛋白可以有效诊断区分健康受试者和过敏性鼻炎患者，诊断准确率高，可以用于开发成诊断过敏性鼻炎的试剂盒，比现有诊断方法客观性明显提高。