Method for catalytic synthesis of double-activity BX/Res ternary grafted esterified biomass nanoparticles by rectorite

• Main Authors: QIAN JINGXIA, LYU YIJU, LIU HUAFENG, YANG JINWU, ZUO KAI, GE WENXU, ZOU ZHIMING, TIAN KEXIN, YANG YINGYING, LI HEPING, LI MINGKUN
• Format: Patent
• Language: Chinese; English
• Published: 04.06.2024
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention discloses a method for catalytic synthesis of double-activity BX/Res ternary grafted esterified biomass nanoparticles by rectorite. A BX/Res compound is used as a raw material, EGDMA and TBMA emulsified by alkyl glycoside are used as mixed grafting monomers, ammonium persulfate is used as an initiator, and the BX/Res ternary grafting derivative is synthesized through free radical polymerization in a water solvent. Carboxyphenylboronic acid is used as an esterifying agent, high-efficiency nanoscale rectorite is used as an esterification catalyst, and carboxyphenylboronic acid and high-efficiency nanoscale rectorite are further subjected to catalytic esterification to synthesize the target product, namely the double-activity BX/Res ternary grafted esterified biomass derivative. And then, preparing the double-activity BX/Res ternary grafted esterified biomass nano-particles through a nano-precipitation method. Molecular docking activity calculation and simulation are respectively carried out on the