Compound containing tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure

The invention relates to a compound containing a tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure. Specifically, the compound disclosed by the invention has a structure as shown in a formula I, and the definitions of all groups and substituent groups are described in the specification. The i...

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Main Authors DING CHUNYONG, XIAO RUOXUAN, MA JING, ZHANG AO, XIAO XUANZHENG
Format Patent
LanguageChinese
English
Published 04.06.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The invention relates to a compound containing a tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure. Specifically, the compound disclosed by the invention has a structure as shown in a formula I, and the definitions of all groups and substituent groups are described in the specification. The invention also discloses a preparation method of the compound and application of the compound in prevention and/or treatment of KRAS mutation related diseases. # imgabs0 # 本发明涉及含四氢吡唑并吡啶[3,4-d]嘧啶结构的化合物。具体地，本发明化合物具有式I所示结构，其中各基团和取代基的定义如说明书中所述。本发明还公开了所述化合物的制备方法及其在预防和/或治疗KRAS突变相关疾病方面的用途。#imgabs0#
AbstractList The invention relates to a compound containing a tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure. Specifically, the compound disclosed by the invention has a structure as shown in a formula I, and the definitions of all groups and substituent groups are described in the specification. The invention also discloses a preparation method of the compound and application of the compound in prevention and/or treatment of KRAS mutation related diseases. # imgabs0 # 本发明涉及含四氢吡唑并吡啶[3,4-d]嘧啶结构的化合物。具体地，本发明化合物具有式I所示结构，其中各基团和取代基的定义如说明书中所述。本发明还公开了所述化合物的制备方法及其在预防和/或治疗KRAS突变相关疾病方面的用途。#imgabs0#
Author XIAO XUANZHENG
ZHANG AO
MA JING
XIAO RUOXUAN
DING CHUNYONG
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Snippet The invention relates to a compound containing a tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure. Specifically, the compound disclosed by the...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Compound containing tetrahydropyrazolopyridine [3, 4-d] pyrimidine structure
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