2, 3-dihydroxy aziridinyl acrylamide DNMA and preparation method thereof

• Main Authors: WANG HENG, ZHUANG XIANJUN, WU HENGSHAN, ZHANG HUYIN, WU LEXIAN, XIAO JIE, SUN SHILIANG
• Format: Patent
• Language: Chinese; English
• Published: 23.02.2024
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention provides 2, 3-dihydroxy aziridinyl acrylamide DNMA and a preparation method thereof, and the preparation method comprises the following steps: S1, preparation of a supported quaternary ammonium base catalyst: carrying out heating reflux reaction on quaternary ammonium salt and hydroxide in an alcoholic solution to obtain the supported quaternary ammonium base catalyst; s2: preparation of 2, 3-dihydroxy aziridinyl acrylamide: taking acrylamide and glyoxal as raw materials to react under the action of the supported quaternary ammonium base catalyst prepared in the step S1, so as to prepare the 2, 3-dihydroxy aziridinyl acrylamide. According to the preparation method disclosed by the invention, the 2, 3-dihydroxy aziridinyl acrylamide DNMA with high purity can be prepared, and the preparation method has relatively high commercial value and popularization value. 本发明提供了一种2,3-二羟基氮丙啶基丙烯酰胺DNMA及其制备方法，所述制备方法包括以下步骤：S1：负载型季铵碱催化剂的制备：将季铵盐在醇溶液中与氢氧化物加热回流反应后得到负载型季铵碱催化剂；S2：2,3-二羟基氮丙啶基丙烯酰胺的制备：在步骤S1制备获得的负载型季铵碱催化剂的作