Novel polymer coating cross-linked alginic acid gel fiber

• Main Authors: FURUSAKO SHOJI, SATO SHINGO, SATO TSUTOMU, NARUMI TOMOHIRO
• Format: Patent
• Language: Chinese; English
• Published: 06.02.2024
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; SPIRITS; VINEGAR; WINE

And a further antibody production method is sought. Provided are: a polymer coating cross-linked alginic acid gel fiber in which a core layer containing antibody-producing cells (e.g., antibody-producing CHO cells) or physiologically active substance-producing cells (e.g., CHO cells) is coated with a cationic polymer; and a method for producing an antibody, a physiologically active substance or the like using the fiber. MIN6 cells from pancreatic beta cells) and a cross-linked alginic acid gel. 寻求进一步的抗体的生产方法。本发明提供：将芯层用阳离子性聚合物被覆的聚合物涂层交联海藻酸凝胶纤维以及使用该纤维的抗体、生理活性物质等的制造方法，所述芯层包含产生抗体的细胞(例如，产生抗体的CHO细胞)或产生生理活性物质的细胞(例如，来自胰岛β细胞的MIN6细胞)和交联海藻酸凝胶。