Treatment of pain in pediatric patients by administration of sustained release liposomal anesthetic compositions

In some embodiments, provided herein is a method of treating pain, the method comprising administering to a subject a pharmaceutical composition comprising: a) a multivesicular liposome comprising: at least one amphiphilic lipid and at least one neutral lipid; and b) an aqueous phase comprising bupi...

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Bibliographic Details
Main Author WINSTON, ROLAND
Format Patent
LanguageChinese
English
Published 29.12.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:In some embodiments, provided herein is a method of treating pain, the method comprising administering to a subject a pharmaceutical composition comprising: a) a multivesicular liposome comprising: at least one amphiphilic lipid and at least one neutral lipid; and b) an aqueous phase comprising bupivacaine phosphate wherein the aqueous phase is encapsulated within the multivesicular liposome. 在一些实施方式中，本文提供了治疗疼痛的方法，所述方法包括向对象给予包含下述的药物组合物：a)多囊泡脂质体，所述多囊泡脂质体包含：至少一种两亲性脂质和至少一种中性脂质；和b)水相，所述水相包括磷酸布比卡因，其中，所述水相被包封在多囊泡脂质体内。
Bibliography:Application Number: CN20228036140