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Abstract The invention provides an application of SC-43 in preparation of a medicine for resisting gram-positive bacterial infection, and the CAS number of the SC-43 is 1400989-25-4; the SC-43 has the effect of inhibiting the growth of gram-positive bacteria and the formation of a biofilm. According to the technical scheme, the novel medical application of the SC-43 is disclosed, and the SC-43 shows better antibacterial activity on various gram-positive bacteria and can remarkably inhibit formation of a biofilm; the antibacterial activity can be comparable with that of Van (vancomycin), and is superior to that of Van, and the biological activity of efficiently killing staphylococcus aureus is reflected; and the SC-43 can influence the permeability of the membrane. 本发明提供了SC-43用于制备抗革兰氏阳性细菌感染药物中的应用,所述SC-43,CAS编号为1400989-25-4;所述SC-43具有抑制革兰氏阳性细菌的生长和生物被膜形成的作用。本发明的技术方案公开了SC-43的医药新用途,SC-43对多种革兰氏阳性细菌表现出较佳的抗菌活性,能够显著抑制生物被膜的形成;具有可与Van(万古霉素)媲美的抑菌活性,且优于Van的杀菌活性,且体现出高效杀灭金黄色葡萄球菌的生物学活性;SC-43可影响膜的通透性。
AbstractList The invention provides an application of SC-43 in preparation of a medicine for resisting gram-positive bacterial infection, and the CAS number of the SC-43 is 1400989-25-4; the SC-43 has the effect of inhibiting the growth of gram-positive bacteria and the formation of a biofilm. According to the technical scheme, the novel medical application of the SC-43 is disclosed, and the SC-43 shows better antibacterial activity on various gram-positive bacteria and can remarkably inhibit formation of a biofilm; the antibacterial activity can be comparable with that of Van (vancomycin), and is superior to that of Van, and the biological activity of efficiently killing staphylococcus aureus is reflected; and the SC-43 can influence the permeability of the membrane. 本发明提供了SC-43用于制备抗革兰氏阳性细菌感染药物中的应用,所述SC-43,CAS编号为1400989-25-4;所述SC-43具有抑制革兰氏阳性细菌的生长和生物被膜形成的作用。本发明的技术方案公开了SC-43的医药新用途,SC-43对多种革兰氏阳性细菌表现出较佳的抗菌活性,能够显著抑制生物被膜的形成;具有可与Van(万古霉素)媲美的抑菌活性,且优于Van的杀菌活性,且体现出高效杀灭金黄色葡萄球菌的生物学活性;SC-43可影响膜的通透性。
Author PENG RENHAI
HUANG JINLIAN
LI WEIFEN
LAN QIQI
YU ZHIJIAN
HE PEIKUN
LI PEIYU
Author_xml – fullname: PENG RENHAI
– fullname: LAN QIQI
– fullname: HUANG JINLIAN
– fullname: LI PEIYU
– fullname: LI WEIFEN
– fullname: HE PEIKUN
– fullname: YU ZHIJIAN
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DocumentTitleAlternate SC-43用于制备抗革兰氏阳性细菌感染药物中的应用
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Snippet The invention provides an application of SC-43 in preparation of a medicine for resisting gram-positive bacterial infection, and the CAS number of the SC-43 is...
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SubjectTerms ADHESIVES
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
CHEMICAL PAINT OR INK REMOVERS
CHEMISTRY
COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS
CORRECTING FLUIDS
DYES
FILLING PASTES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
INKS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
PAINTS
PASTES OR SOLIDS FOR COLOURING OR PRINTING
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
POLISHES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TRAPPING
USE OF MATERIALS THEREFOR
WOODSTAINS
Title Application of SC-43 in preparation of gram-positive bacterial infection resisting medicine
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