2, 3-diketopiperazine derivative of salt thereof

The present invention relates to a 2,3-diketopiperazine derivative or a salt thereof, which has inhibitory effect on platelet aggregation because of glycoprotein IIb/IIIa receptor antagonism and hence is useful as a prophylactic and therapeutic agent for diseases associated with platelet aggregation...

Full description

Saved in:
Bibliographic Details
Main Authors YAMAMOTO HIROHIKO, YAMAFUJI TETSUO, ONO SATOSHI
Format Patent
LanguageEnglish
Published 14.01.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract The present invention relates to a 2,3-diketopiperazine derivative or a salt thereof, which has inhibitory effect on platelet aggregation because of glycoprotein IIb/IIIa receptor antagonism and hence is useful as a prophylactic and therapeutic agent for diseases associated with platelet aggregation. General formula: wherein R represents a protected or unprotected amidino group; R represents a hydrogen atom or a carboxyl-protecting group; A represents a substituted or unsubstituted lower alkylene group; B represents -O-, -CONH-, -NHCO- or -SO2NH-; Y represents a substituted or unsubstituted lower alkylene group; and the broken line represents a single bond or a double bond.
AbstractList The present invention relates to a 2,3-diketopiperazine derivative or a salt thereof, which has inhibitory effect on platelet aggregation because of glycoprotein IIb/IIIa receptor antagonism and hence is useful as a prophylactic and therapeutic agent for diseases associated with platelet aggregation. General formula: wherein R represents a protected or unprotected amidino group; R represents a hydrogen atom or a carboxyl-protecting group; A represents a substituted or unsubstituted lower alkylene group; B represents -O-, -CONH-, -NHCO- or -SO2NH-; Y represents a substituted or unsubstituted lower alkylene group; and the broken line represents a single bond or a double bond.
Author YAMAMOTO HIROHIKO
ONO SATOSHI
YAMAFUJI TETSUO
Author_xml – fullname: YAMAMOTO HIROHIKO
– fullname: YAMAFUJI TETSUO
– fullname: ONO SATOSHI
BookMark eNrjYmDJy89L5WQwMNJRMNZNycxOLckvyCxILUqsysxLVUhJLcosSyzJLEtVyE9TKE7MKVEoyUgtSs1P42FgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c5-hobmBiYGlo7GhFUAAGioK7s
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
Edition 6
ExternalDocumentID CN1170409A
GroupedDBID EVB
ID FETCH-epo_espacenet_CN1170409A3
IEDL.DBID EVB
IngestDate Fri Jul 19 13:58:13 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CN1170409A3
Notes Application Number: CN19951096903
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980114&DB=EPODOC&CC=CN&NR=1170409A
ParticipantIDs epo_espacenet_CN1170409A
PublicationCentury 1900
PublicationDate 19980114
PublicationDateYYYYMMDD 1998-01-14
PublicationDate_xml – month: 01
  year: 1998
  text: 19980114
  day: 14
PublicationDecade 1990
PublicationYear 1998
RelatedCompanies TOYAMA CHEMICAL CO., LTD
RelatedCompanies_xml – name: TOYAMA CHEMICAL CO., LTD
Score 2.4835372
Snippet The present invention relates to a 2,3-diketopiperazine derivative or a salt thereof, which has inhibitory effect on platelet aggregation because of...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title 2, 3-diketopiperazine derivative of salt thereof
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980114&DB=EPODOC&locale=&CC=CN&NR=1170409A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3dS8MwED_mFPVNpzK_-yB9Mthm2Ucfiri0ZQjrhkzZ22ibKxZlLWvVf98krurL3kIClw9yubskv98B3PSwn0adlBE2iCPCUguJE3eR9FEae-EgRVT3kOOwN3pmj_PuvAGvNRZG84R-aXJEqVGJ1PdKn9fF3yWWp_9WlndxJqvy-2Dmeqao4WLKvze9oetPJ96Em5y7PDTDJ1clWJGhzMMWbCsnWrHs-y9DhUkp_huU4AB2plLWsjqEBi5bsMfrvGst2B2vn7tlca155RFY9NboEJG9YZUXWYErTQttCLmBPjV3t5GnRhm9V4by6DBPj-E68Gd8RGTXi99ZLnhYj7FzAk0Z-2MbDGROgiJN7GSAjFInooIyYaFyo2xLiFNob5JytrnpHPZ_oHU2sdkFNKvVB15K21rFV3pZvgGMu37z
link.rule.ids 230,309,786,891,25594,76904
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1LT8MwDLbGQIwbDNB4rgfUExF9ZI8eKsTSTQXWbkID7Ta1jSsm0FptBf4-SViBy25RIjkPxbGd5PsMcNXGThrZKSW0G0eEpgYSJ24h6aAw9txBC1HeQwZh23-mD9PWtAKvJRZG8YR-KXJEoVGJ0PdCndf53yWWp_5Wrm7iuajKbgcT19N5CReT_r3u9dz-eOSNmM6Yy0I9fHJlghURytxtwXZHBISSZb__0pOYlPy_QRnsw85YyFoUB1DBRR1qrMy7VofdYP3cLYprzVsdgmFdazbh8zcssnye41LRQmtcbKBPxd2tZam2it4LTXp0mKVH0Bz0J8wnouvZ7yxnLCzHaB9DVcT-2AANqZMgTxMz6SK1LCeyuEW5gdKNMg3OT6CxScrp5qYm1PxJMJwN78PHM9j7gdmZxKTnUC2WH3gh7GwRX6ol-gahs4He
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=2%2C+3-diketopiperazine+derivative+of+salt+thereof&rft.inventor=YAMAMOTO+HIROHIKO&rft.inventor=YAMAFUJI+TETSUO&rft.inventor=ONO+SATOSHI&rft.date=1998-01-14&rft.externalDBID=A&rft.externalDocID=CN1170409A