Derivatization detection method for sulfonyl isocyanate chloride

• Main Authors: WEN XIANMING, GAO XU, YANG QIANG, XIONG XUEWU
• Format: Patent
• Language: Chinese; English
• Published: 15.09.2023
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention provides a derivatization detection method of isocyanate sulfonyl chloride. The derivatization detection method comprises the following steps: preparing a reference solution and a test solution; the method comprises the following steps: mixing a derivatization reagent with a solution containing a set content of isocyanate chlorosulfonyl ester, and reacting at room temperature to obtain a reference substance solution; the method comprises the following steps: mixing a derivatization reagent with a test sample, and reacting at room temperature to obtain a test sample solution; the derivatization reagent is obtained by dissolving 1-methylpiperazine in an organic solvent; respectively analyzing the reference substance solution and the test solution by adopting a liquid chromatograph-mass spectrometer, recording chromatograms, and calculating the content of 1-methylpiperazine sulfonamide according to a peak area external standard method in combination with the content of the isocyanate sulfuryl chlor