Bifidobacterium adolescentis strain and application thereof

• Main Authors: ZHANG HENAN, WU JUNRUI, SHI HAISU, SUN ERNA, ZHAI QIXIAO, SHI YUDONG, ZHANG LANWEI, WU RINA, LI SHUSEN
• Format: Patent
• Language: Chinese; English
• Published: 05.09.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The invention provides bifidobacterium adolescentis and application thereof, and belongs to the technical field of probiotics. The preservation number of the bifidobacterium adolescentis is CGMCC (China General Microbiological Culture Collection Center) No.25046, and the bifidobacterium adolescentis can tolerate a gastrointestinal fluid environment of a human body and has relatively good adhesion capability and oxidation resistance; and a plurality of oligosaccharides can be utilized, and can be colonized in intestinal tracts to play a long-acting role. The strain is sensitive to various antibiotics, has biological safety, has remarkable bacteriostatic ability to escherichia coli O157: H7, can improve the weight loss condition of mice during the disease period of bacterial colitis, improves the food intake of the mice, has a repairing effect on colonic epithelial tissues, increases the number of colonic goblet cells of the mice, reduces inflammation infiltration, and has a good anti-inflammatory effect on the