Preparation method of gallic acid catalyzed by sulfinic acid or sulfonic acid derivative

• Main Authors: LIU YIWEN, CHEN QINGLONG, NING RAN, MAO YEFU, CHEN CHIQING, XIE SHANYU, ZHAN XIANG
• Format: Patent
• Language: Chinese; English
• Published: 18.08.2023
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention relates to the technical field of chemical engineering and biological medicines, in particular to a preparation method of gallic acid catalyzed by sulfinic acid or sulfonic acid derivatives, which specifically comprises the following steps: adding tannic acid or a raw material containing tannic acid, water and a catalyst into a reaction flask, uniformly mixing, heating to 100-110 DEG C, heating to react, and mixing and stirring for 2-3 hours; adding hydrochloric acid to adjust Ph after the reaction is finished, filtering while hot, cooling and crystallizing to obtain a crude product; and recrystallizing the crude product to obtain a gallic acid product. The invention optimizes and improves the traditional alkaline process, explores a novel gallic acid preparation method, and uses commercial inorganic salt sodium sulfite as a catalyst to catalyze the hydrolysis of tannic acid, tara, gallnut and the like to prepare gallic acid. Compared with a traditional alkaline process, the method is mild in ca