Pharmaceutical composition for preventing or treating wounds or scars comprising benzbromarone

• Main Authors: LIM DONGUL, PARK JUNG-KYU
• Format: Patent
• Language: Chinese; English
• Published: 25.07.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides a pharmaceutical composition for preventing or treating wounds or scars, comprising benzbromarone as an active ingredient. The present invention has proved that benzbromarone inhibits the function of heat shock protein 47 (HSP47), and has found that benzbromarone can inhibit collagen accumulation by reducing collagen overproduction cells, thereby preventing or treating wounds or scars. Therefore, the composition comprising benzbromarone as an active ingredient of the present invention can be effectively used in the medical and pharmaceutical fields for preventing or treating wounds or scars. 本发明提供了用于预防或治疗伤口或疤痕的药物组合物，包括作为活性成分的苯溴马隆。本发明已经证实了苯溴马隆抑制热休克蛋白47(HSP47)的功能，并且已经发现苯溴马隆可以通过减少胶原过度生成细胞来抑制胶原的积聚，从而预防或治疗伤口或疤痕。因此，本发明的包括作为活性成分的苯溴马隆的组合物可以有效地用于医疗和药物领域用于预防或治疗伤口或疤痕。