Novel compounds

The present invention relates to novel compounds useful as inhibitors of NLRP3 inflammasome production wherein such compounds are as defined by compounds of formula (I), and wherein the whole R1, R2 and R3 are defined in the specification, and wherein these compounds can be used as medicaments, for...

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Main Authors VAN LOMPE DIRK, LANCANFI MICHELE, VAN OPDEN BOSCH NIELS, OEHLRICH DANIEL, VAN GOOL MARCELLINUS L. M, TRESADERN GARY JOHN, LABELLIACROS JORGE
Format Patent
LanguageChinese
English
Published 30.05.2023
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Abstract The present invention relates to novel compounds useful as inhibitors of NLRP3 inflammasome production wherein such compounds are as defined by compounds of formula (I), and wherein the whole R1, R2 and R3 are defined in the specification, and wherein these compounds can be used as medicaments, for example, in the treatment of diseases or disorders associated with NLRP3 inflammasome activity. 本发明涉及用作NLRP3炎症小体产生抑制剂的新型化合物,其中这样的化合物如通过具有式(I)的化合物所定义,并且其中完整体R1、R2和R3在本说明书中所定义,并且其中这些化合物可以用作药剂,例如用于治疗与NLRP3炎症小体活性相关的疾病或障碍。
AbstractList The present invention relates to novel compounds useful as inhibitors of NLRP3 inflammasome production wherein such compounds are as defined by compounds of formula (I), and wherein the whole R1, R2 and R3 are defined in the specification, and wherein these compounds can be used as medicaments, for example, in the treatment of diseases or disorders associated with NLRP3 inflammasome activity. 本发明涉及用作NLRP3炎症小体产生抑制剂的新型化合物,其中这样的化合物如通过具有式(I)的化合物所定义,并且其中完整体R1、R2和R3在本说明书中所定义,并且其中这些化合物可以用作药剂,例如用于治疗与NLRP3炎症小体活性相关的疾病或障碍。
Author LABELLIACROS JORGE
VAN GOOL MARCELLINUS L. M
VAN OPDEN BOSCH NIELS
OEHLRICH DANIEL
TRESADERN GARY JOHN
LANCANFI MICHELE
VAN LOMPE DIRK
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– fullname: TRESADERN GARY JOHN
– fullname: LABELLIACROS JORGE
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Snippet The present invention relates to novel compounds useful as inhibitors of NLRP3 inflammasome production wherein such compounds are as defined by compounds of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title Novel compounds
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