Preparation method of salicyl fluorescent ketone

• Main Authors: HUA JIAJUN, ZHOU YONG, CHEN CHENG
• Format: Patent
• Language: Chinese; English
• Published: 12.05.2023
• Subjects: ADHESIVES; CHEMISTRY; DYES; HETEROCYCLIC COMPOUNDS; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; POLISHES

The invention discloses a preparation method of salicyl fluorescein, which comprises the following steps: S1, mixing 1, 2, 4-trihydroxybenzene acetate, ethanol and concentrated sulfuric acid, heating to 70-80 DEG C, adding salicylaldehyde, stirring and reacting at constant temperature for 3-5 hours, and cooling reaction liquid to room temperature; s2, oxygen is continuously introduced into the reaction liquid cooled to the room temperature in the step S1, a precipitate is separated out through a reaction, the precipitate is washed and subjected to suction filtration, solid matter obtained through suction filtration is dried, and salicyl fluorescein is obtained; wherein in the step S2, in the reaction process, oxygen is continuously introduced into the reaction liquid, the speed of introducing the oxygen into the reaction liquid is 100-300 ml/min, and the reaction time is 16-40 h. The preparation method of the salicyl fluorescein has the advantages of short preparation route, mild reaction conditions, low reac