Aspergillus sydowii BTBU20213012 as well as metabolic compound and application thereof

• Main Authors: DONG YIFEI, SONG FUXING, LIU XINYU, LI HONGHUA
• Format: Patent
• Language: Chinese; English
• Published: 11.04.2023
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention provides an aspergillus sydowii BTBU20213012, a metabolic compound of the aspergillus sydowii BTBU20213012 and an application of the aspergillus sydowii BTBU20213012 and belongs to the technical field of microbial metabolism, and the preservation number of the aspergillus sydowii BTBU20213012 is CGMCC (China General Microbiological Culture Collection Center) NO.40156. The invention also provides a compound for inhibiting staphylococcus aureus, which can be prepared from the aspergillus sydowii BTBU20213012 through fermentation culture, extraction and chromatographic column separation. The invention also provides a specific structure of the separated compound. According to the present invention, the minimum inhibitory concentration of the compound obtained through the metabolism of the aspergillus sydowii BTBU20213012 on staphylococcus aureus is 200 [mu] g/mL; 本发明提供了一种聚多曲霉菌BTBU20213012及其代谢化合物和应用，属于微生物代谢技术领域，所述的聚多曲霉菌BTBU20213012的保藏号为CGMCC NO.40156。本发明还提供了所述聚多曲霉菌BTBU20213012经发酵培养、萃取、色谱柱分离，可制备得到抑制金黄