Methods and products for treating gastrointestinal disorders

• Main Authors: GERARDIN YANNICK, TAYLOR EDWARD, SMITH MARK, GALOULAKIS KOSMAS, VO ANH-TUAN E, HUNSCHE JURGEN, SADOWSKI RADOSLAW, TIMBLECK STEPHEN
• Format: Patent
• Language: Chinese; English
• Published: 11.04.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Described herein are compositions and methods for delivering microbial therapeutic agents useful for the treatment of conditions associated with dysbacteriosis of intestinal flora. In various aspects, the present invention provides compositions and methods useful for treating or preventing inflammatory bowel disease (IBD) in a subject in need thereof. For example, the present invention relates, in part, to a plurality of bacterial isolates wherein at least two of the plurality of bacterial isolates are isolated from faeces of different human donors. 本文描述用于递送微生物治疗剂的组合物和方法，所述微生物治疗剂可用于治疗与肠道菌群失调有关的病症。在各个方面，本发明提供了可用于治疗或预防有需要的受试者的炎症性肠病(IBD)的组合物和方法。例如，本发明部分涉及多种细菌分离株，其中所述多种细菌分离株中的至少两种是从不同人类供体的粪便分离。