Cellulose-based hydrogel composite material loaded with nano-zinc oxide and menthol

• Main Authors: JIANG LIHUI, HAN YUHENG, WANG TING
• Format: Patent
• Language: Chinese; English
• Published: 07.04.2023
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

The invention belongs to the technical field of composite cellulose materials, and relates to preparation of a cellulose-based hydrogel composite material loaded with nano-zinc oxide and menthol. According to the composite material, hydroxyethyl cellulose is used as a matrix of hydrogel, and soluble cyclodextrin host molecules with cationic groups can be uniformly embedded into gaps of a cellulose material; menthol with antibacterial, pain-relieving and itching-relieving effects is wrapped by cyclodextrin, so that the water solubility is increased, and a slow-release effect is achieved; nano-zinc oxide with antibacterial and wound healing promoting functions is adsorbed by cationic groups and is uniformly distributed on the surface of cellulose. The composite material disclosed by the invention has a huge application prospect in the field of wound dressings. 本发明属于复合纤维素材料技术领域，涉及制备一种负载纳米氧化锌及薄荷醇的纤维素基水凝胶复合材料。该复合材料以羟乙基纤维素作为水凝胶的基质，带有阳离子基团的可溶性环糊精主体分子可以均匀地嵌入到纤维素材料的空隙中；具有抗菌、止痛、止痒作用的薄荷醇被环糊精包裹而增加了水溶性并且具有缓释的效果；具有抗菌、促进伤口愈