Application of polygala tenuifolia extract in treating attention deficit hyperactivity disorder

• Main Authors: JIANG CANGXUAN, DONG JIUYUAN, JIN QIXIN, WU XIANMIN
• Format: Patent
• Language: Chinese; English
• Published: 04.04.2023
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to the use of a composition comprising a polygala tenuifola Will plant extract (e.g., PDC-1421) for the preparation of a pharmaceutical product for the treatment of attention deficit hyperactivity disorder (ADHD). The composition comprises a polygala tenuifola Will plant extract, e.g., PDC-1421. The composition of the present invention can be prepared into a gelatin capsule, and oral administration of the composition at a daily dose of between 380 mg and 3800 mg in a healthy subject is safe and well tolerant. The composition can be taken for at least 25 days for a long time; the daily dosage can be one time a day, two times a day or three times a day, and each dose contains 380-760 mg of the plant extract. 本发明关于一种包含远志(Polygala tenuifoliaWilld)植物萃取物(如PDC-1421)的组合物用于制备治疗注意力不足过动症(ADHD)的医药品的用途。本发明的组合物可制备成一种明胶胶囊，且于健康受试者中，以介于380mg至3800mg的每日剂量口服该组合物是安全且耐受良好的。本发明的组合物可长期服用至少25天；每日剂量可以一日一次、一日两次或一日三次的方式投药，其中每剂含有380-760mg的植物萃取物。