Application of IOWH-032 in preparation of gram-positive bacterial infection resisting medicine

• Main Authors: PENG RENHAI, LAN QIQI, HUANG JINLIAN, MAO TING, LI PEIYU, YU ZHIJIAN
• Format: Patent
• Language: Chinese; English
• Published: 31.03.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides an application of IOWH-032 in preparation of a medicine for resisting gram-positive bacterial infection, and the CAS number of the IOWH-032 is 1191252-49-9. The invention also provides an application of the IOWH-032 in preparation of a medicine for resisting gram-positive bacterial infection. According to the technical scheme, the novel medical application of the IOWH-032 is disclosed, the IOWH-032 has a powerful inhibiting effect on gram-positive bacteria, growth of bacteria such as staphylococcus aureus, enterococcus faecalis and staphylococcus epidermidis and formation of biofilms can be inhibited, and the IOWH-032 can be used for preparing the medicine for treating the diseases such as the staphylococcus aureus, the enterococcus faecalis and the staphylococcus epidermidis. And the compound shows certain activity of killing staphylococcus aureus and enterococcus faecalis in gram-positive bacteria. 本发明提供了IOWH-032用于制备抗革兰氏阳性细菌感染药物中的应用，所述IOWH-032，CAS编号为1191252-49-9。本发明的技术方案公开了IOWH-032的医药