Ox-bile-resistant bezoar transforming bacterium and application thereof
The invention belongs to the field of resource development and utilization of oxgall-resistant bezoar transforming bacteria, and particularly relates to an oxgall-resistant bezoar transforming bacterium and application thereof. The characteristic base sequence of 16S rDNA of the oxgall-resistant bez...
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Main Authors | , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
28.03.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The invention belongs to the field of resource development and utilization of oxgall-resistant bezoar transforming bacteria, and particularly relates to an oxgall-resistant bezoar transforming bacterium and application thereof. The characteristic base sequence of 16S rDNA of the oxgall-resistant bezoar transformed bacterium is shown as SEQ No.1, characteristic base sites comprise 265-A, 275-C, 280-G, 282-A, 537-A and 581-A, the oxgall-resistant bezoar transformed bacterium is unique oxgall citrobacter, and the preservation number of the strain is CGMCC No.24893. The oxgall-resistant bezoar transformed bacterium is applied to fermentation production of in-vitro cultured bezoar, and the content of bilirubin and cholic acid fermented at 30 DEG C for 16 days is increased by more than two times compared with that of natural oxgall. The strain NDZNM-01 disclosed by the invention can tolerate oxgall with a broad-spectrum bacteriostatic effect, the survival time in pure oxgall is longer than 9 days, the survival time |
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Bibliography: | Application Number: CN202211125844 |