Quantitative method for non-targeted screening of perfluorinated and polyfluoroalkyl compounds

• Main Authors: LIU YI, CHEN QIAN, HU JINGRUN, NI JINREN, SUN WEILING, XIAO XINZONG, ZHANG TONGYING, WANG SHULEI
• Format: Patent
• Language: Chinese; English
• Published: 08.11.2022
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention discloses a quantitative method for non-targeted screening of perfluorinated and polyfluoroalkyl compounds. The quantitative method comprises the following steps: carrying out solid-phase extraction and nitrogen blowing concentration to obtain a sample extracting solution; performing non-targeted screening on the perfluoro and polyfluoroalkyl compounds in the extracting solution to obtain a perfluoro and polyfluoroalkyl compound screening list; establishing a prediction model by using the response factors and the molecular descriptors of the perfluorinated and polyfluoroalkyl compound standard samples; and predicting response factors of the standard-sample-free perfluorinated and polyfluoroalkyl compounds by using the constructed prediction model, and calculating the concentrations of the standard-sample-free perfluorinated and polyfluoroalkyl compounds. According to the method, accurate quantification of the perfluorinated and polyfluoroalkyl compound with the standard sample is realized by com