Skull repair plate capable of promoting bone tissue regeneration and preparation method thereof

• Main Authors: ZHANG HAIJUN, REN JINPING, YUAN KUNSHAN
• Format: Patent
• Language: Chinese; English
• Published: 14.10.2022
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; TREATMENT OR PROTECTION OF EYES OR EARS

The invention discloses a skull repair plate capable of promoting bone tissue regeneration and a preparation method of the skull repair plate, and belongs to the technical field of medical instruments, the skull repair plate has an innovative concentric circle structure and a three-layer sandwich structure, and controllability of the pore-forming rate and the bone fusion rate can be achieved by controlling structural composition; due to the addition of mineralized collagen, calcium and phosphorus ions are released in the degradation process, osteoblast proliferation can be promoted, meanwhile, pores are formed through degradation, and a space is provided for bone tissue regeneration and fusion; on the other hand, the mechanical property of the mineralized collagen can be improved by adding the magnetic nanoparticles, and meanwhile, the magnetic nanoparticles serving as a micro magnetic source can generate continuous and stable magnetic stimulation to promote proliferation and differentiation of bone cells. 本发