Active polysaccharide compound extracted from pitaya stems as well as preparation method and application of active polysaccharide compound

• Main Authors: TANG YAYUAN, HE XUEMEI, YI PING, LIU GUOMING, CHEN QIAN, RAO CHUANYAN, LI CHANGBAO, SUN JIAN, WEI ZHEN, SHENG JINFENG
• Format: Patent
• Language: Chinese; English
• Published: 16.09.2022
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention belongs to the technical field of polysaccharide preparation, and particularly relates to an active polysaccharide compound extracted from pitaya stems, the chemical structural formula of the active polysaccharide compound is shown in the specification, and the molecular weight of the active polysaccharide compound is 134.282 kDa; the active polysaccharide compound is a compound composed of rhamnose, galactose and galacturonic acid according to a molar ratio of 1.00: 11.94: 3.05. The invention also provides a preparation method of the active polysaccharide compound and application of the active polysaccharide compound in anti-hepatoma drugs. The steps for preparing the active polysaccharide compound are simple, and the prepared active polysaccharide compound has better anti-hepatoma activity. 本发明属于多糖制备技术领域，具体涉及从火龙果茎中提取的活性多糖类化合物，所述活性多糖类化合物的组分化学结构式为：所述活性多糖类化合物的分子量为134.282kDa；所述活性多糖类化合物为摩尔比为1.00:11.94:3.05的鼠李糖、半乳糖和半乳糖醛酸组成的化合物。本发明还提供上述活性多糖类化合物的制备方法及其在抗肝癌药物中的应用。本发明制备活性多糖类化合物的步骤简单，且制备得到的活性多糖类化合物具有较佳的抗